Don't pull the plug! the Drosophila mating plug preserves fertility

Platelet membrane potential: unable to pull the plug on sepsis

In a recent issue of Critical Care, we read with interest the work of Gründler and colleagues [1] regarding platelet mitochondrial depolarization reflecting disease severity in patients with sepsis. It has been established that, regardless of the source of sepsis, microcirculatory dysfunction with increased permeability and increased reactive oxygen species is similar among pathogens and leads ...

Innovation Exit: Why Entrepreneurs Pull the Plug on their Innovations

Don't pull the plug on brain death just yet.

In this issue of Tradition, Dr. J. Kunin reviews the medical literature relating to the anatomical and physiological studies of the brain dead patient. Based on the medical evidence that there remain both physiological function and some anatomical integrity of the brain in these patients, he argues that the original halakhic legal decisions accepting brain death as halakhic death need to be re-...

Yank: Enabling Green Data Centers to Pull the Plug

Balancing a data center’s reliability, cost, and carbon emissions is challenging. For instance, data centers designed for high availability require a continuous flow of power to keep servers powered on, and must limit their use of clean, but intermittent, renewable energy sources. In this paper, we present Yank, which uses transient server abstraction to maintain server availability, while allo...

Retention of Ejaculate by Drosophila melanogaster Females Requires the Male-Derived Mating Plug Protein PEBme.

Within the mated reproductive tracts of females of many taxa, seminal fluid proteins (SFPs) coagulate into a structure known as the mating plug (MP). MPs have diverse roles, including preventing female remating, altering female receptivity postmating, and being necessary for mated females to successfully store sperm. The Drosophila melanogaster MP, which is maintained in the mated female for se...